Improvement of pyridoxine-induced peripheral neuropathy by Cichorium intybus hydroalcoholic extract through GABAergic system
نویسندگان
چکیده
منابع مشابه
Prevention of oxidative stress-induced apoptosis of C2C12 myoblasts by a Cichorium intybus root extract.
Cell injury associated with reactive oxygen species (ROS) has been reported in various muscular disorders. We found that a Cichorium intybus (Cii) extract reduced H(2)O(2)-induced viability loss in C2C12 myoblasts, inhibited oxidative stress-induced apoptosis and increased intracellular heat shock protein 70 (Hsp 70) expression. Cii also inhibited the level of intracellular ceramide. These resu...
متن کاملHydroalcoholic extract of needles of Pinus eldarica enhances pentobarbital-induced sleep: possible involvement of GABAergic system
Objective: Insomnia is accompanied by several health complications and the currently used soporific drugs can induce several side effects such as psychomotor impairment, amnesia, and tolerance. The present study was planned to investigate the sleep prolonging effect of Pinus eldarica. Materials and Methods: Hydroalcoholic extract (HAE) of P. eldarica, its water fraction (WF), ethyl acetate frac...
متن کاملHydroalcoholic extract of needles of Pinus eldarica enhances pentobarbital-induced sleep: possible involvement of GABAergic system
OBJECTIVE Insomnia is accompanied by several health complications and the currently used soporific drugs can induce several side effects such as psychomotor impairment, amnesia, and tolerance. The present study was planned to investigate the sleep prolonging effect of Pinus eldarica. MATERIALS AND METHODS Hydroalcoholic extract (HAE) of P. eldarica, its water fraction (WF), ethyl acetate frac...
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Trigonella foenum graecum commonly known as Fenugreek exerts normoglycemic and insulinotropic effects in humans by compounds from its seed and leaf extracts. Some studies reported that treating pregnant mice with fenugreek seed could cause toxic effects on the nervous system of its pubs during developmental growth, while in some other studies neuroprotective properties were considered for it. S...
متن کاملAntibacterial and antifungal study of Cichorium intybus
Therapeutic or medicinal plants are very beneficial for economic and therapeutic purposes. These plants contain active constituents which are used for the rehabilitation of many human diseases. These constituents are isolated and used against various pathogens[1,2]. Cichorium intybus (C. intybus ) seeds have been successfully used in Ayurvedic and Unani systems of medicine. It is one of the imp...
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ژورنال
عنوان ژورنال: The Journal of Physiological Sciences
سال: 2019
ISSN: 1880-6546,1880-6562
DOI: 10.1007/s12576-019-00659-8